职称: 博士、教授、博士生导师
职务: 华南肿瘤学国家重点实验室PI
专长: 探寻肿瘤治疗新药物靶点,新治疗策略,开发精准有效的联合用药组合。以及诱导肿瘤细胞衰老和Senolytic药物的研发。
王力勤师从Rene Bernards教授, 在荷兰癌症研究所完成博士学位与博士后研究。2021年在荷兰癌症研究所担任Associate staff scientist。 2022年获得国家级高层次人才青年项目,中山大学“百人计划”引进人才资助,担任中山大学肿瘤防治中心研究员。迄今,以第一作者身份或通讯在Nature Reviews Cancer (封面论文), Nature Reviews Drug Discovery, Cell,Nature, Nature Cancer, European Urology 等国际著名学术期刊发表多篇论文,其中2项研究成果获批进入临床试验研究阶段,也取得相关国际发明专利2项。获荷兰教育部优秀留学生Delta奖学金,中国留学基金委国家优秀自费留学生奖学金,荷兰皇家化学协会H.G.K.Westenbrink Prize(全荷兰每年一位名额)。
主要研究方向:
探寻肿瘤治疗新药物靶点,新治疗策略,开发精准有效的联合用药组合。以及诱导肿瘤细胞衰老和Senolytic药物的研发。
代表性论文 (#第一作者,*通讯作者)
Liqin Wang#, Lina Lankhorst, René Bernards*. Exploiting senescence for the treatment of cancer. Nature Reviews Cancer. 2022(封面论文, IF: 69.8)
Haojie Jin*, Liqin Wang*, René Bernards*. Rational combinations of targeted cancer therapies: background, advances and challenges. Nature Reviews Drug Discovery. 2022(IF: 112)
Liqin Wang# *, Haojie Jin, Fleur Jochems, Siying Wang, Cor Lieftink, Isabel Mora Martinez, Giulia De Conti, Finn Edwards, Rodrigo Leite de Oliveira, Arnout Schepers, Yangyang Zhou, Jiaojiao Zheng, Wei Wu, Xingling Zheng, Shengxian Yuan, Jing Ling, Kathy Jastrzebski, Matheus Dos Santos Dias, Ji-Ying Song, Patrick N. H. Celie, Hideo Yagita, Ming Yao, Weiping Zhou, Roderick L. Beijersbergen, Wenxin Qin*, René Bernards*. cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis. Nature Cancer. 2022(IF: 22)
Liqin Wang#, Rodrigo Leite de Oliveira#, Sanne Huijberts, Evert Bosdriesz, Nora Pencheva, Diede Brunen, Astrid Bosma, Ji-Ying Song, John Zevenhoven, G. Tjitske Los-de Vries, Hugo Horlings, Bastiaan Nuijen, Jos H. Beijnen, Jan H.M. Schellens, Rene Bernards*. An acquired vulnerability of drug-resistant melanoma with therapeutic potential. Cell. 2018(IF: 67)
Chong Sun#, Liqin Wang#, Sidong Huang#, Guus J. J. E. Heynen, Anirudh Prahallad, Caroline Robert, John Haanen, Christian Blank, Jelle Wesseling, Stefan M. Willems, Davide Zecchin, Sebastijan Hobor, Prashanth K. Bajpe, Cor Lieftink, Christina Mateus, Stephan Vagner, Wipawadee Grernrum, Ingrid Hofland, Andreas Schlicker, Lodewyk F. A. Wessels, Roderick L. Beijersbergen, Alberto Bardelli, Federica Di Nicolantonio, Alexander M. M. Eggermont, Rene Bernards*. Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma. Nature. 2014(IF: 69)
更新时间:2023年1月9日